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Furthermore, ADA activity is elevated in T2DM patients and may serve as a marker of inflammation and obesity (29)
Reported side effects have been gastrointestinal symptoms, such as nausea, vomiting, diarrhea, constipation, and abdominal discomfort
(3) Fat synthesis, high-density lipoprotein (HDL) formation, liver HDL uptake, and fatty acid -oxidation, are affected, disrupting lipid metabolism and worsening liver steatosis and fibrosis (Ding et al., 2015)
Researchers caution that many of the studies remain in early stages and that significant questions remain unanswered, particularly for children and adolescents whose brains are still developing
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